Fibroblast migration correlates with matrix softness. A study in knob-hole engineered fibrin

The invasion of a matrix by migrating cells is a key step in its remodelling. At least in 2D migration models, cells tend to localize in stiffer areas (durotaxis). Here, we show that mechanical properties affect differently the 3D migration rate: non-proteolytic 3D cell migration is facilitated in s...

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Detalles Bibliográficos
Autores principales: Leon-Valdivieso, Christopher Y., Wedgwood, Jennifer, Lallana, Enrique, Donno, Roberto, Roberts, Iwan, Ghibaudi, Matilde, Tirella, Annalisa, Tirelli, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481723/
https://www.ncbi.nlm.nih.gov/pubmed/31069320
http://dx.doi.org/10.1063/1.5022841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481723/
https://www.ncbi.nlm.nih.gov/pubmed/31069320
http://dx.doi.org/10.1063/1.5022841

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