FGF-2 inhibits contractile properties of valvular interstitial cell myofibroblasts encapsulated in 3D MMP-degradable hydrogels

Valvular interstitial cells (VICs) are responsible for the maintenance of the extracellular matrix in heart valve leaflets and, in response to injury, activate from a quiescent fibroblast to a wound healing myofibroblast phenotype. Under normal conditions, myofibroblast activation is transient, but...

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Detalles Bibliográficos
Autores principales: Gonzalez Rodriguez, Andrea, Schroeder, Megan E., Walker, Cierra J., Anseth, Kristi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481727/
https://www.ncbi.nlm.nih.gov/pubmed/31069326
http://dx.doi.org/10.1063/1.5042430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481727/
https://www.ncbi.nlm.nih.gov/pubmed/31069326
http://dx.doi.org/10.1063/1.5042430

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