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Synthesis and targeting of gold-coated (177)Lu-containing lanthanide phosphate nanoparticles—A potential theranostic agent for pulmonary metastatic disease

Targeted radiotherapies maximize cytotoxicity to cancer cells. In this work, we describe the synthesis, characterization, and biodistribution of antibody conjugated gold-coated lanthanide phosphate nanoparticles containing (177)Lu. [(177)Lu]Lu(0.5)Gd(0.5)(PO(4))@Au@PEG(800)@Ab nanoparticles combine...

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Detalles Bibliográficos
Autores principales: Sobol, Nicholas, Sutherlin, Logan, Cedrowska, Edyta, Schorp, Joshua, Rodríguez-Rodríguez, Cristina, Sossi, Vesna, Lattimer, Jimmy, Miller, Douglas C, Pevsner, Paul, Robertson, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481741/
https://www.ncbi.nlm.nih.gov/pubmed/31069286
http://dx.doi.org/10.1063/1.5018165