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TLR1/2 orchestrate human plasmacytoid predendritic cell response to gram+ bacteria
Gram+ infections are worldwide life-threatening diseases in which the pathological role of type I interferon (IFN) has been highlighted. Plasmacytoid predendritic cells (pDCs) produce high amounts of type I IFN following viral sensing. Despite studies suggesting that pDCs respond to bacteria, the me...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481764/ https://www.ncbi.nlm.nih.gov/pubmed/31017904 http://dx.doi.org/10.1371/journal.pbio.3000209 |