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TLR1/2 orchestrate human plasmacytoid predendritic cell response to gram+ bacteria

Gram+ infections are worldwide life-threatening diseases in which the pathological role of type I interferon (IFN) has been highlighted. Plasmacytoid predendritic cells (pDCs) produce high amounts of type I IFN following viral sensing. Despite studies suggesting that pDCs respond to bacteria, the me...

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Detalles Bibliográficos
Autores principales: Raieli, Salvatore, Trichot, Coline, Korniotis, Sarantis, Pattarini, Lucia, Soumelis, Vassili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481764/
https://www.ncbi.nlm.nih.gov/pubmed/31017904
http://dx.doi.org/10.1371/journal.pbio.3000209