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Cross-species alcohol dependence-associated gene networks: Co-analysis of mouse brain gene expression and human genome-wide association data

Genome-wide association studies on alcohol dependence, by themselves, have yet to account for the estimated heritability of the disorder and provide incomplete mechanistic understanding of this complex trait. Integrating brain ethanol-responsive gene expression networks from model organisms with hum...

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Detalles Bibliográficos
Autores principales: Mignogna, Kristin M., Bacanu, Silviu A., Riley, Brien P., Wolen, Aaron R., Miles, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481773/
https://www.ncbi.nlm.nih.gov/pubmed/31017905
http://dx.doi.org/10.1371/journal.pone.0202063