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MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis

Staphylococcus aureus is able to infect virtually all organ systems and is a frequently isolated etiologic agent of osteomyelitis, a common and debilitating invasive infection of bone. Treatment of osteomyelitis requires invasive surgical procedures and prolonged antibiotic therapy, yet is frequentl...

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Detalles Bibliográficos
Autores principales: Putnam, Nicole E., Fulbright, Laura E., Curry, Jacob M., Ford, Caleb A., Petronglo, Jenna R., Hendrix, Andrew S., Cassat, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481883/
https://www.ncbi.nlm.nih.gov/pubmed/30978245
http://dx.doi.org/10.1371/journal.ppat.1007744