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MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis
Staphylococcus aureus is able to infect virtually all organ systems and is a frequently isolated etiologic agent of osteomyelitis, a common and debilitating invasive infection of bone. Treatment of osteomyelitis requires invasive surgical procedures and prolonged antibiotic therapy, yet is frequentl...
Autores principales: | Putnam, Nicole E., Fulbright, Laura E., Curry, Jacob M., Ford, Caleb A., Petronglo, Jenna R., Hendrix, Andrew S., Cassat, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481883/ https://www.ncbi.nlm.nih.gov/pubmed/30978245 http://dx.doi.org/10.1371/journal.ppat.1007744 |
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