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The N-terminus of Sec61p plays key roles in ER protein import and ERAD

Sec61p is the channel-forming subunit of the heterotrimeric Sec61 complex that mediates co-translational protein import into the endoplasmic reticulum (ER). In yeast, proteins can also be post-translationally translocated by the hetero-heptameric Sec complex, composed of the Sec61 and the Sec63 comp...

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Detalles Bibliográficos
Autores principales: Elia, Francesco, Yadhanapudi, Lalitha, Tretter, Thomas, Römisch, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481919/
https://www.ncbi.nlm.nih.gov/pubmed/31017954
http://dx.doi.org/10.1371/journal.pone.0215950