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Incidence and clinicopathologic features of H3 K27M mutations in adults with radiographically-determined midline gliomas

PURPOSE: H3 K27 mutations, most commonly in H3F3A, are common in diffuse midline glioma. The exact frequency of these mutations in adults with gliomas in the midline location is unknown. This study was conducted to define the incidence of H3 K27M mutations in this location and to compare clinicopath...

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Detalles Bibliográficos
Autores principales: Schreck, Karisa C., Ranjan, Surabhi, Skorupan, Nebojša, Bettegowda, Chetan, Eberhart, Charles G., Ames, Heather M., Holdhoff, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482123/
https://www.ncbi.nlm.nih.gov/pubmed/30864101
http://dx.doi.org/10.1007/s11060-019-03134-x