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Ensuring expression of four core cardiogenic transcription factors enhances cardiac reprogramming

Previous studies have shown that forced expression of core cardiogenic transcription factors can directly reprogram fibroblasts to induced cardiomyocyte-like cells (iCMs). This cardiac reprogramming approach suggests a potential strategy for cardiomyocyte regeneration. However, a major challenge of...

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Detalles Bibliográficos
Autores principales: Zhang, Zhentao, Zhang, Alexander D., Kim, Luke J., Nam, Young-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482135/
https://www.ncbi.nlm.nih.gov/pubmed/31019236
http://dx.doi.org/10.1038/s41598-019-42945-w