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In vivo synaptic activity-independent co-uptakes of amyloid β(1–42) and Zn(2+) into dentate granule cells in the normal brain
Neuronal amyloid β(1–42) (Aβ(1–42)) accumulation is considered an upstream event in Alzheimer’s disease pathogenesis. Here we report the mechanism on synaptic activity-independent Aβ(1–42) uptake in vivo. When Aβ(1–42) uptake was compared in hippocampal slices after incubating with Aβ(1–42), In vitr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482136/ https://www.ncbi.nlm.nih.gov/pubmed/31019269 http://dx.doi.org/10.1038/s41598-019-43012-0 |