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Evidence of Different IL-1β Activation Pathways in Innate Immune Cells From Indeterminate and Cardiac Patients With Chronic Chagas Disease

Background: Chagas cardiomyopathy is the main fibrosing myocarditis among known heart diseases. Development of cardiomyopathy has been related to extracellular matrix (ECM) remodeling, which are controlled by matrix metalloproteinases (MMPs) and cytokines, especially interleukin (IL)-1β. The convert...

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Detalles Bibliográficos
Autores principales: Medeiros, Nayara I., Pinto, Bruna F., Elói-Santos, Silvana M., Teixeira-Carvalho, Andréa, Magalhães, Luísa M. D., Dutra, Walderez O., Correa-Oliveira, Rodrigo, Gomes, Juliana A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482163/
https://www.ncbi.nlm.nih.gov/pubmed/31057540
http://dx.doi.org/10.3389/fimmu.2019.00800