Cargando…
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival
Malignant melanoma is one of the most difficult cancers to treat due to its resistance to chemotherapy. Despite recent successes with BRAF inhibitors and immune checkpoint inhibitors, many patients do not respond or become resistant to these drugs. Hence, alternative treatments are still required. D...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482196/ https://www.ncbi.nlm.nih.gov/pubmed/31019203 http://dx.doi.org/10.1038/s41419-019-1568-3 |