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The Functional and Molecular Effects of Doxycycline Treatment on Borrelia burgdorferi Phenotype

Recent studies have shown that Borrelia burgdorferi can form antibiotic-tolerant persisters in the presence of microbiostatic drugs such as doxycycline. Precisely how this occurs is yet unknown. Our goal was to examine gene transcription by B. burgdorferi following doxycycline treatment in an effort...

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Detalles Bibliográficos
Autores principales: Caskey, John R., Hasenkampf, Nicole R., Martin, Dale S., Chouljenko, Vladimir N., Subramanian, Ramesh, Cheslock, Mercedes A., Embers, Monica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482230/
https://www.ncbi.nlm.nih.gov/pubmed/31057493
http://dx.doi.org/10.3389/fmicb.2019.00690