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Germline Predisposition and Copy Number Alteration in Pre-stage Lung Adenocarcinomas Presenting as Ground-Glass Nodules

Objective: Synchronous multiple ground-glass nodules (SM-GGNs) are a distinct entity of lung cancer which has been emerging increasingly in recent years in China. The oncogenesis molecular mechanisms of SM-GGNs remain elusive. Methods: We investigated single nucleotide variations (SNV), insertions a...

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Detalles Bibliográficos
Autores principales: Ren, Yijiu, Huang, Shujun, Dai, Chenyang, Xie, Dong, Zheng, Larry, Xie, Huikang, Zheng, Hui, She, Yunlang, Zhou, Fangyu, Wang, Yue, Li, Pengpeng, Fei, Ke, Jiang, Gening, Zhang, Yang, Su, Bo, Sweet-Cordero, E. Alejandro, Tran, Nhan Le, Yang, Yanan, Patel, Jai N., Rolfo, Christian, Rocco, Gaetano, Cardona, Andrés Felipe, Tuzi, Alessandro, Suter, Matteo B., Yang, Ping, Xu, Wayne, Chen, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482264/
https://www.ncbi.nlm.nih.gov/pubmed/31058088
http://dx.doi.org/10.3389/fonc.2019.00288