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TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter
TonEBP is a key transcriptional activator in macrophages with an M1 phenotype. High expression of TonEBP is associated with many inflammatory diseases. Heme oxygenase-1 (HO-1), a stress-inducible protein, is induced by various oxidative and inflammatory signals, and its expression is regarded as an...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482272/ https://www.ncbi.nlm.nih.gov/pubmed/31057560 http://dx.doi.org/10.3389/fimmu.2019.00850 |