A Retrospective Evaluation of Allometry, Population Pharmacokinetics, and Physiologically‐Based Pharmacokinetics for Pediatric Dosing Using Clearance as a Surrogate

Physiologically‐based pharmacokinetic models are increasingly applied for pediatric dose selection along with traditional methods such as allometry and population pharmacokinetic models. We report a retrospective evaluation of the three methods. Pediatric population pharmacokinetic models sourced fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Qier, Peters, Sheila Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482279/
https://www.ncbi.nlm.nih.gov/pubmed/30762304
http://dx.doi.org/10.1002/psp4.12385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482279/
https://www.ncbi.nlm.nih.gov/pubmed/30762304
http://dx.doi.org/10.1002/psp4.12385

Ejemplares similares