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Peptone‐mediated glucagon‐like peptide‐1 secretion depends on intestinal absorption and activation of basolaterally located Calcium‐Sensing Receptors

Protein intake robustly stimulates the secretion of the incretin hormone, glucagon‐like peptide‐1 (GLP‐1) but the molecular mechanisms involved are not well understood. In particular, it is unknown whether proteins stimulate secretion by activation of luminal or basolateral sensors. We characterized...

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Detalles Bibliográficos
Autores principales: Modvig, Ida M., Kuhre, Rune E., Holst, Jens Juul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482282/
https://www.ncbi.nlm.nih.gov/pubmed/31020803
http://dx.doi.org/10.14814/phy2.14056