Formation of dendrimer-guest complexes as a strategy to increase the solubility of a phenazine N, N′-dioxide derivative with antitumor activity

Poly(amidoamine) and Poly(propylenimine) dendrimers with different generations and peripheral groups were studied as solubility enhancers and nanocarriers for 7-bromo-2-hydroxy-phenazine N(5),N(10)-dioxide. This compound possesses potential antitumoral and anti-trypanosomal activity, but its low sol...

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Detalles Bibliográficos
Autores principales: Dib, Nahir, Fernández, Luciana, Santo, Marisa, Otero, Luis, Alustiza, Fabrisio, Liaudat, Ana Cecilia, Bosch, Pablo, Lavaggi, M. Laura, Cerecetto, Hugo, González, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482317/
https://www.ncbi.nlm.nih.gov/pubmed/31049437
http://dx.doi.org/10.1016/j.heliyon.2019.e01528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482317/
https://www.ncbi.nlm.nih.gov/pubmed/31049437
http://dx.doi.org/10.1016/j.heliyon.2019.e01528

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