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Formation of dendrimer-guest complexes as a strategy to increase the solubility of a phenazine N, N′-dioxide derivative with antitumor activity
Poly(amidoamine) and Poly(propylenimine) dendrimers with different generations and peripheral groups were studied as solubility enhancers and nanocarriers for 7-bromo-2-hydroxy-phenazine N(5),N(10)-dioxide. This compound possesses potential antitumoral and anti-trypanosomal activity, but its low sol...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482317/ https://www.ncbi.nlm.nih.gov/pubmed/31049437 http://dx.doi.org/10.1016/j.heliyon.2019.e01528 |