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Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration
The adult zebrafish is capable of regenerating heart muscle, resolving collagen tissue, and fully restoring heart function throughout its life. In this study, we show that the highly upregulated, epicardium-enriched microRNA let-7i functions in wound closure and cardiomyocyte proliferation. RNA sequ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482333/ https://www.ncbi.nlm.nih.gov/pubmed/31026665 http://dx.doi.org/10.1016/j.isci.2019.04.009 |