Peroxiredoxin-mediated disulfide bond formation is required for nucleocytoplasmic translocation and secretion of HMGB1 in response to inflammatory stimuli

The nuclear protein HMGB1 (high mobility group box 1) is secreted by monocytes-macrophages in response to inflammatory stimuli and serves as a danger-associated molecular pattern. Acetylation and phosphorylation of HMGB1 are implicated in the regulation of its nucleocytoplasmic translocation for sec...

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Detalles Bibliográficos
Autores principales: Kwak, Man Sup, Kim, Hee Sue, Lkhamsuren, Khulan, Kim, Young Hun, Han, Myeong Gil, Shin, Jae Min, Park, In Ho, Rhee, Woo Joong, Lee, Se Kyoung, Rhee, Sue Goo, Shin, Jeon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482348/
https://www.ncbi.nlm.nih.gov/pubmed/31026770
http://dx.doi.org/10.1016/j.redox.2019.101203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482348/
https://www.ncbi.nlm.nih.gov/pubmed/31026770
http://dx.doi.org/10.1016/j.redox.2019.101203

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