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Metabolic engineering of Escherichia coli BL21 (DE3) for de novo production of l-DOPA from d-glucose
BACKGROUND: Production of l-tyrosine is gaining grounds as the market size of 3,4-dihydroxyphenyl-l-alanine (l-DOPA) is expected to increase due to increasing cases of Parkinson’s disease a neurodegenerative disease. Attempts to overproduce l-tyrosine for conversion to l-DOPA has stemmed on the over...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482505/ https://www.ncbi.nlm.nih.gov/pubmed/31023316 http://dx.doi.org/10.1186/s12934-019-1122-0 |