BRCA1 mRNA expression modifies the effect of T cell activation score on patient survival in breast cancer

BACKGROUND: Effector CD8(+) T cell activation and its cytotoxic function to eradicate tumor cells depend on the T cell recognition of tumor neoantigens, and are positively associated with improved survival in breast cancer. Tumor suppressor BRCA1 and cell cycle regulator CCND1 play a critical role i...

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Detalles Bibliográficos
Autores principales: Lu, Lingeng, Huang, Huatian, Zhou, Jing, Ma, Wenxue, Mackay, Sean, Wang, Zuoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482542/
https://www.ncbi.nlm.nih.gov/pubmed/31023256
http://dx.doi.org/10.1186/s12885-019-5595-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482542/
https://www.ncbi.nlm.nih.gov/pubmed/31023256
http://dx.doi.org/10.1186/s12885-019-5595-3

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