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BRCA1 mRNA expression modifies the effect of T cell activation score on patient survival in breast cancer
BACKGROUND: Effector CD8(+) T cell activation and its cytotoxic function to eradicate tumor cells depend on the T cell recognition of tumor neoantigens, and are positively associated with improved survival in breast cancer. Tumor suppressor BRCA1 and cell cycle regulator CCND1 play a critical role i...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482542/ https://www.ncbi.nlm.nih.gov/pubmed/31023256 http://dx.doi.org/10.1186/s12885-019-5595-3 |