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Increasing Upstream Chromatin Long–Range Interactions May Favor Induction of Circular RNAs in LysoPC-Activated Human Aortic Endothelial Cells

Circular RNAs (circRNAs) are non-coding RNAs that form covalently closed continuous loops, and act as gene regulators in physiological and disease conditions. To test our hypothesis that proatherogenic lipid lysophosphatidylcholine (LPC) induce a set of circRNAs in human aortic endothelial cell (HAE...

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Detalles Bibliográficos
Autores principales: Li, Angus, Sun, Yu, Drummer, Charles, Lu, Yifan, Yu, Daohai, Zhou, Yan, Li, Xinyuan, Pearson, Simone J., Johnson, Candice, Yu, Catherine, Yang, William Y., Mastascusa, Kevin, Jiang, Xiaohua, Sun, Jianxin, Rogers, Thomas, Hu, Wenhui, Wang, Hong, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482593/
https://www.ncbi.nlm.nih.gov/pubmed/31057422
http://dx.doi.org/10.3389/fphys.2019.00433