Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload

The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and the recapitulation of disease pathologies. Here, in a cardiac tissue model consisting of filamentous 3D matr...

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Detalles Bibliográficos
Autores principales: Ma, Zhen, Huebsch, Nathaniel, Koo, Sangmo, Mandegar, Mohammad A., Siemons, Brian, Boggess, Steven, Conklin, Bruce R., Grigoropoulos, Costas P., Healy, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482859/
https://www.ncbi.nlm.nih.gov/pubmed/31015724
http://dx.doi.org/10.1038/s41551-018-0280-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482859/
https://www.ncbi.nlm.nih.gov/pubmed/31015724
http://dx.doi.org/10.1038/s41551-018-0280-4

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