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Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload
The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and the recapitulation of disease pathologies. Here, in a cardiac tissue model consisting of filamentous 3D matr...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482859/ https://www.ncbi.nlm.nih.gov/pubmed/31015724 http://dx.doi.org/10.1038/s41551-018-0280-4 |