Cargando…

Secondary amines as coupling partners in direct catalytic asymmetric reductive amination

The secondary amine participating asymmetric reductive amination remains an unsolved problem in organic synthesis. Here we show for the first time that secondary amines are capable of effectively serving as N-sources in direct asymmetric reductive amination to afford corresponding tertiary chiral am...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zitong, Du, Shaozhi, Gao, Guorui, Yang, Wenkun, Yang, Xiongyu, Huang, Haizhou, Chang, Mingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482873/
https://www.ncbi.nlm.nih.gov/pubmed/31057780
http://dx.doi.org/10.1039/c9sc00323a