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Therapeutically Attenuating Neutrophil Recruitment With a CXCR2 Antagonist in Combination With Oseltamivir Ameliorates Influenza-Induced Lung Injury and Disease

Mice were infected with influenza and treated with a CXCR2 antagonist in combination with antiviral or antiviral alone starting 4 days postinfection. Neutrophil recruitment to the lung was reduced, and improvements in health outcomes and lung consolidation were observed in combination-treated mice w...

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Detalles Bibliográficos
Autores principales: Washburn, Michael L, Crosby, Renae, Remlinger, Katja, Wang, Feng, Creech, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483135/
https://www.ncbi.nlm.nih.gov/pubmed/31041337
http://dx.doi.org/10.1093/ofid/ofz106