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Single cell RNA sequencing reveals regional heterogeneity of hepatobiliary innate lymphoid cells in a tissue-enriched fashion

IL-33 promotes type 2 immunity, epithelial repair, and tissue fibrosis by activating group 2 innate lymphoid cells (ILC2). ILC2 lack all known surface markers of mature T, B, NK, and myeloid cell lineages (Lin(neg)), express the IL-33 receptor ST2, and release type 2 cytokines which contribute to ch...

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Detalles Bibliográficos
Autores principales: Peters, Anna L., Luo, Zhenhua, Li, Jun, Mourya, Reena, Wang, Yunguan, Dexheimer, Phillip, Shivakumar, Pranav, Aronow, Bruce, Bezerra, Jorge A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483339/
https://www.ncbi.nlm.nih.gov/pubmed/31022195
http://dx.doi.org/10.1371/journal.pone.0215481