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Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation

The urinary metabolites (Z)-7-[1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid (8-iso-PGF(2α)), an F2-isoprostane and biomarker of oxidative damage, and “prostaglandin E(2) metabolite” (PGE-M), a biomarker of inflammation, are elevated in cigarette smokers. How...

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Detalles Bibliográficos
Autores principales: Carmella, Steven G., Heskin, Alisa K., Tang, Mei Kuen, Jensen, Joni, Luo, Xianghua, Le, Chap T., Murphy, Sharon E., Benowitz, Neal L., McClernon, F. Joseph, Vandrey, Ryan, Allen, Sharon S., Denlinger-Apte, Rachel, Cinciripini, Paul M., Strasser, Andrew A., al’Absi, Mustafa, Robinson, Jason D., Donny, Eric C., Hatsukami, Dorothy K., Hecht, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483352/
https://www.ncbi.nlm.nih.gov/pubmed/31022220
http://dx.doi.org/10.1371/journal.pone.0215853