Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing

RNA polymerase II (Pol II) pausing is a general regulatory step in transcription, yet the stability of paused Pol II varies widely between genes. Although paused Pol II stability correlates with core promoter elements, the contribution of individual sequences remains unclear, in part because no rapi...

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Detalles Bibliográficos
Autores principales: Shao, Wanqing, Alcantara, Sergio G-M, Zeitlinger, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483594/
https://www.ncbi.nlm.nih.gov/pubmed/31021316
http://dx.doi.org/10.7554/eLife.41461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483594/
https://www.ncbi.nlm.nih.gov/pubmed/31021316
http://dx.doi.org/10.7554/eLife.41461

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