Genetic diversity of cytochrome P450 3A with different metabolic activity in domestic cats

Knowledge on genetic polymorphisms of metabolising enzymes including cytochrome P450 (CYP) is very limited in cats. We investigated polymorphisms in CYP3A131, one of the major CYP isoforms in the feline liver and small intestine. Eight non-synonymous variants and one synonymous variant of feline CYP...

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Detalles Bibliográficos
Autores principales: SUGIYAMA, Souta, UNO, Yasuhiro, AMANO, Tomoko, KITAZAWA, Takio, TERAOKA, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483910/
https://www.ncbi.nlm.nih.gov/pubmed/30828039
http://dx.doi.org/10.1292/jvms.18-0692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483910/
https://www.ncbi.nlm.nih.gov/pubmed/30828039
http://dx.doi.org/10.1292/jvms.18-0692

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