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How to increase our belief in discovered statistical interactions via large-scale association studies?

The understanding that differences in biological epistasis may impact disease risk, diagnosis, or disease management stands in wide contrast to the unavailability of widely accepted large-scale epistasis analysis protocols. Several choices in the analysis workflow will impact false-positive and fals...

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Detalles Bibliográficos
Autores principales: Van Steen, K., Moore, J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483943/
https://www.ncbi.nlm.nih.gov/pubmed/30840129
http://dx.doi.org/10.1007/s00439-019-01987-w