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SIRT1 inhibits monocyte adhesion to the vascular endothelium by suppressing Mac-1 expression on monocytes

SIRT1 signaling pathways modulate vascular inflammation; however, the precise role of SIRT1 in monocyte adhesion to the vascular endothelium, a key event initiating vascular inflammation, is unclear. Thus, this study investigated the roles and molecular interaction of SIRT1 and TLR2 in regulating mo...

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Detalles Bibliográficos
Autores principales: Lee, Seung Jin, Baek, Seung Eun, Jang, Min A., Kim, Chi Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483987/
https://www.ncbi.nlm.nih.gov/pubmed/31023999
http://dx.doi.org/10.1038/s12276-019-0239-x