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Sensory primary cilium is a responsive cAMP microdomain in renal epithelia

Primary cilia are hair-like cellular extensions that sense microenvironmental signals surrounding cells. The role of adenylyl cyclases in ciliary function has been of interest because the product of adenylyl cyclase activity, cAMP, is relevant to cilia-related diseases. In the present study, we show...

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Detalles Bibliográficos
Autores principales: Sherpa, Rinzhin T., Mohieldin, Ashraf M., Pala, Rajasekharreddy, Wachten, Dagmar, Ostrom, Rennolds S., Nauli, Surya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484033/
https://www.ncbi.nlm.nih.gov/pubmed/31024067
http://dx.doi.org/10.1038/s41598-019-43002-2