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FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression

F-box only protein 8 (FBX8), as a critical component of the SKP1-CUL1-F-box (SCF) E3 ubiquitin ligases, has been associated with several malignancies through interacting with a member of proteins. However, the substrates of FBX8 for destruction in the progression of colorectal carcinoma (CRC) need t...

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Detalles Bibliográficos
Autores principales: FeiFei, Wang, HongHai, Xu, YongRong, Yan, PingXiang, Wu, JianHua, Wu, XiaoHui, Zhu, JiaoYing, Li, JingBo, Sun, Kun, Zhou, XiaoLi, Ren, Lu, Qi, XiaoLiang, Lan, ZhiQiang, Cheng, Na, Tang, WenTing, Liao, YanQing, Ding, Li, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484082/
https://www.ncbi.nlm.nih.gov/pubmed/31024008
http://dx.doi.org/10.1038/s41419-019-1588-z