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Low-Dose Tacrolimus Prevents Dysregulated Peri-Conceptional Ovarian and Systemic Immune Cellular Homeostasis in Subjects with PCOS

Polycystic ovary syndrome (PCOS) is characterized by failure of ovulation and is associated with obesity and chronic inflammation. Recent evidence suggests that anomalous activation of ovarian macrophages and numerical and functional deficits in the Th17 (CD4+IL17A+) and the CD4+CD25+CD127(low) Treg...

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Detalles Bibliográficos
Autores principales: Albaghdadi, Ahmad J. H., Feeley, Carolyn Ann, Kan, Frederick W. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484102/
https://www.ncbi.nlm.nih.gov/pubmed/31024070
http://dx.doi.org/10.1038/s41598-019-42960-x