Cerebral mitochondrial electron transport chain dysfunction in multiple system atrophy and Parkinson’s disease

Multiple system atrophy (MSA) is a neurodegenerative disease characterised by glial cytoplasmic inclusions (GCIs), containing α-synuclein. Mutated COQ2, encoding an enzyme essential for co-enzyme Q10 (CoQ10) biosynthesis, has been associated with MSA. CoQ10 is an electron carrier in the mitochondria...

Descripción completa

Detalles Bibliográficos
Autores principales: Foti, Sandrine C., Hargreaves, Iain, Carrington, Stephanie, Kiely, Aoife P., Houlden, Henry, Holton, Janice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484105/
https://www.ncbi.nlm.nih.gov/pubmed/31024027
http://dx.doi.org/10.1038/s41598-019-42902-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484105/
https://www.ncbi.nlm.nih.gov/pubmed/31024027
http://dx.doi.org/10.1038/s41598-019-42902-7

Ejemplares similares