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Cerebral mitochondrial electron transport chain dysfunction in multiple system atrophy and Parkinson’s disease

Multiple system atrophy (MSA) is a neurodegenerative disease characterised by glial cytoplasmic inclusions (GCIs), containing α-synuclein. Mutated COQ2, encoding an enzyme essential for co-enzyme Q10 (CoQ10) biosynthesis, has been associated with MSA. CoQ10 is an electron carrier in the mitochondria...

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Detalles Bibliográficos
Autores principales:	Foti, Sandrine C., Hargreaves, Iain, Carrington, Stephanie, Kiely, Aoife P., Houlden, Henry, Holton, Janice L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484105/ https://www.ncbi.nlm.nih.gov/pubmed/31024027 http://dx.doi.org/10.1038/s41598-019-42902-7

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