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Method to identify efficiently cleaved, membrane-bound, functional HIV-1 (Human Immunodeficiency Virus-1) envelopes

An ideal vaccine against HIV-1 will specifically elicit bNAbs (broadly neutralizing antibodies) which can cross-neutralize a wide spectrum of circulating viral strains belonging to different clades. The current paradigm for developing such a vaccine is to generate HIV-1 envelope (Env)-based immunoge...

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Detalles Bibliográficos
Autores principales: Samal, Sweety, Bansal, Manish, Das, Supratik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484210/
https://www.ncbi.nlm.nih.gov/pubmed/31049300
http://dx.doi.org/10.1016/j.mex.2019.04.013