Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback

Branching patterns and regulatory networks differ between branched organs. It has remained unclear whether a common regulatory mechanism exists and how organ-specific patterns can emerge. Of all previously proposed signalling-based mechanisms, only a ligand-receptor-based Turing mechanism based on F...

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Detalles Bibliográficos
Autores principales: Menshykau, Denis, Michos, Odyssé, Lang, Christine, Conrad, Lisa, McMahon, Andrew P., Iber, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484223/
https://www.ncbi.nlm.nih.gov/pubmed/30651543
http://dx.doi.org/10.1038/s41467-018-08212-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484223/
https://www.ncbi.nlm.nih.gov/pubmed/30651543
http://dx.doi.org/10.1038/s41467-018-08212-8

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