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DAXX, as a Tumor Suppressor, Impacts DNA Damage Repair and Sensitizes BRCA-Proficient TNBC Cells to PARP Inhibitors()

Treatment options are limited for patients with triple negative breast cancer (TNBC). Understanding genes that participate in cancer progression and DNA damage response (DDR) may improve therapeutic strategies for TNBC. DAXX, a death domain-associated protein, has been reported to be critically invo...

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Detalles Bibliográficos
Autores principales: Shi, Yaqin, Jin, Juan, Wang, Xin, Ji, Wenfei, Guan, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484230/
https://www.ncbi.nlm.nih.gov/pubmed/31029033
http://dx.doi.org/10.1016/j.neo.2019.04.001