rSJYB1 inhibits collagen type I protein expression in hepatic stellate cells via down‐regulating activity of collagen α1 (I) promoter

YB1 is a negative regulator in liver fibrosis. We wondered whether SJYB1, a homologous protein of YB1 from Schistosoma japonicum, has an effect on liver fibrosis in vitro. Recombinant SJYB1 (rSJYB1) protein was expressed in a bacterial system and purified by Ni‐NTA His·Bind Resin. A human hepatic st...

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Detalles Bibliográficos
Autores principales: Chen, Liuting, Ji, Zhaodong, Duan, Lian, Zhu, Dandan, Chen, Jinling, Sun, Xiaolei, Yu, Yang, Duan, Yinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484296/
https://www.ncbi.nlm.nih.gov/pubmed/30895719
http://dx.doi.org/10.1111/jcmm.14271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484296/
https://www.ncbi.nlm.nih.gov/pubmed/30895719
http://dx.doi.org/10.1111/jcmm.14271

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