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Laminin promotes differentiation of rat embryonic stem cells into cardiomyocytes by activating the integrin/FAK/PI3K p85 pathway

The generation of germline competent rat embryonic stem cells (rESCs) allows the study of their lineage commitment. Here, we developed a highly efficient system for rESC‐derived cardiomyocytes, and even the formation of three‐dimensional (3D)‐like cell clusters with cTNT and α‐Actinin. We have valid...

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Detalles Bibliográficos
Autores principales: Wang, Duo, Wang, Yumei, Liu, Huan, Tong, Chang, Ying, Qilong, Sachinidis, Agapios, Li, Li, Peng, Luying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484303/
https://www.ncbi.nlm.nih.gov/pubmed/30907509
http://dx.doi.org/10.1111/jcmm.14264