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Targeting the ROS/PI3K/AKT/HIF‐1α/HK2 axis of breast cancer cells: Combined administration of Polydatin and 2‐Deoxy‐d‐glucose

It is well established that cancer cells depend upon aerobic glycolysis to provide the energy they need to survive and proliferate. However, anti‐glycolytic agents have yielded few positive results in human patients, in part due to dose‐limiting side effects. Here, we discovered the unexpected anti‐...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Zhu, Xinying, Wu, Haichong, Jiang, Kangfeng, Zhao, Gan, Shaukat, Aftab, Deng, Ganzhen, Qiu, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484306/
https://www.ncbi.nlm.nih.gov/pubmed/30920152
http://dx.doi.org/10.1111/jcmm.14276