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Predicting overall survival of patients with hepatocellular carcinoma using a three‐category method based on DNA methylation and machine learning

Hepatocellular carcinoma (HCC) is closely associated with abnormal DNA methylation. In this study, we analyzed 450K methylation chip data from 377 HCC samples and 50 adjacent normal samples in the TCGA database. We screened 47,099 differentially methylated sites using Cox regression as well as SVM‐R...

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Detalles Bibliográficos
Autores principales: Dong, Rui‐Zhao, Yang, Xuan, Zhang, Xin‐Yu, Gao, Ping‐Ting, Ke, Ai‐Wu, Sun, Hui‐chuan, Zhou, Jian, Fan, Jia, Cai, Jia‐bin, Shi, Guo‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484308/
https://www.ncbi.nlm.nih.gov/pubmed/30784182
http://dx.doi.org/10.1111/jcmm.14231