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Predicting overall survival of patients with hepatocellular carcinoma using a three‐category method based on DNA methylation and machine learning
Hepatocellular carcinoma (HCC) is closely associated with abnormal DNA methylation. In this study, we analyzed 450K methylation chip data from 377 HCC samples and 50 adjacent normal samples in the TCGA database. We screened 47,099 differentially methylated sites using Cox regression as well as SVM‐R...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484308/ https://www.ncbi.nlm.nih.gov/pubmed/30784182 http://dx.doi.org/10.1111/jcmm.14231 |