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miR‐148a inhibits early relapsed colorectal cancers and the secretion of VEGF by indirectly targeting HIF‐1α under non‐hypoxia/hypoxia conditions

Vascular endothelial growth factor (VEGF) is correlated with angiogenesis and early relapse of colorectal cancer (CRC). This study investigated the role of miR‐148a in the regulation of VEGF/angiogenesis and early relapse of CRC. We established a stable clone with miR‐148a expression in HCT116 and H...

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Detalles Bibliográficos
Autores principales: Tsai, Hsiang‐Lin, Miao, Zhi‐Feng, Chen, Yi‐Ting, Huang, Ching‐Wen, Yeh, Yung‐Sung, Yang, I‐Ping, Wang, Jaw‐Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484316/
https://www.ncbi.nlm.nih.gov/pubmed/30834693
http://dx.doi.org/10.1111/jcmm.14257